Tranexamic acid and rosuvastatin in patients at risk of cardiovascular events after noncardiac surgery: a pilot of the POISE-3 randomized controlled trial

BACKGROUND: Surgical bleeding is associated with postoperative cardiovascular complications. The efficacy and safety of tranexamic acid (TXA) in noncardiac surgery are still uncertain. Statins may prevent perioperative cardiovascular complications. We conducted a pilot to assess the feasibility of a...

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Pubblicato in:Pilot Feasibility Stud
Autori principali: Marcucci, Maura, Duceppe, Emmanuelle, Le Manach, Yannick, Kearon, Clive, Eikelboom, John W., Pohl, Kayla, Vincent, Jessica, Darvish-Kazem, Saeed, Srinathan, Sadeesh K., Neary, John D. D., Parlow, Joel L., Kurz, Andrea, Gross, Peter L., Mrkobrada, Marko, Balasubramanian, Kumar, Sessler, Daniel I., Devereaux, P. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372857/
https://ncbi.nlm.nih.gov/pubmed/32699643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40814-020-00643-9
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