Targeting Immunometabolism Mediated by CD73 Pathway in EGFR-Mutated Non-small Cell Lung Cancer: A New Hope for Overcoming Immune Resistance

Despite the relevant antitumor efficacy of immunotherapy in advanced non-small cell lung cancer (NSCLC), the results in patients whose cancer harbors activating epidermal growth factor receptor (EGFR) mutations are disappointing. The biological mechanisms underlying immune escape and both unresponsi...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Passarelli, Anna, Aieta, Michele, Sgambato, Alessandro, Gridelli, Cesare
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371983/
https://ncbi.nlm.nih.gov/pubmed/32760402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01479
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