Intracellular interplay between cholecystokinin and leptin signalling for satiety control in rats

Cholecystokinin (CCK) and leptin are satiety-controlling peptides, yet their interactive roles remain unclear. Here, we addressed this issue using in vitro and in vivo models. In rat C6 glioma cells, leptin pre-treatment enhanced Ca(2+) mobilization by a CCK agonist (CCK-8s). This leptin action was...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Koizumi, Hayato, Mohammad, Shahid, Ozaki, Tomoya, Muto, Kiyokazu, Matsuba, Nanami, Kim, Juhyon, Pan, Weihong, Morioka, Eri, Mochizuki, Takatoshi, Ikeda, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371863/
https://ncbi.nlm.nih.gov/pubmed/32686770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69035-6
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