Activin-A Induces Fewer, but Larger Osteoclasts From Monocytes in Both Healthy Controls and Fibrodysplasia Ossificans Progressiva Patients

Fibrodysplasia Ossificans Progressiva (FOP) is a rare genetic disease characterized by heterotopic ossification (HO) that occurs in muscle tissue, tendons, and ligaments. The disease is caused by mutations in the Activin receptor type I (ACVR1) gene resulting in enhanced responsiveness to Activin-A....

Full description

Saved in:
Bibliographic Details
Published in:Front Endocrinol (Lausanne)
Main Authors: Schoenmaker, Ton, Botman, Esmée, Sariyildiz, Merve, Micha, Dimitra, Netelenbos, Coen, Bravenboer, Nathalie, Kelder, Angele, Eekhoff, E. Marelise W., De Vries, Teun J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Endocrinology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371852/
https://ncbi.nlm.nih.gov/pubmed/32760351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00501
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items