Activin-A Induces Fewer, but Larger Osteoclasts From Monocytes in Both Healthy Controls and Fibrodysplasia Ossificans Progressiva Patients

Fibrodysplasia Ossificans Progressiva (FOP) is a rare genetic disease characterized by heterotopic ossification (HO) that occurs in muscle tissue, tendons, and ligaments. The disease is caused by mutations in the Activin receptor type I (ACVR1) gene resulting in enhanced responsiveness to Activin-A....

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Publicat a:Front Endocrinol (Lausanne)
Autors principals: Schoenmaker, Ton, Botman, Esmée, Sariyildiz, Merve, Micha, Dimitra, Netelenbos, Coen, Bravenboer, Nathalie, Kelder, Angele, Eekhoff, E. Marelise W., De Vries, Teun J.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Endocrinology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371852/
https://ncbi.nlm.nih.gov/pubmed/32760351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00501
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