FKS1 mutation associated with decreased echinocandin susceptibility of Aspergillus fumigatus following anidulafungin exposure

Invasive aspergillosis (IA) is a potentially lethal infection that affects mostly immunocompromised patients caused by Aspergillus fumigatus. Echinocandins are a second-line therapy against IA, used as a salvage therapy as well as for empirical or prophylactic therapy. Although they cause lysis of g...

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Publicado no:Sci Rep
Main Authors: e Silva, Ana Pinto, Miranda, Isabel Marcos, Branco, Joana, Oliveira, Patricia, Faria-Ramos, Isabel, Silva, Raquel M., Rodrigues, Acácio Gonçalves, Costa-de-Oliveira, Sofia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371691/
https://ncbi.nlm.nih.gov/pubmed/32686741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68706-8
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