Alu-Mediated MEN1 Gene Deletion and Loss of Heterozygosity in a Patient with Multiple Endocrine Neoplasia Type 1

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder caused by mutations of the tumor suppressor gene MEN1. Most of the germline MEN1 gene mutations have been small mutations, and the whole gene deletion is rarely observed. In the present study, we revealed Alu retrotransposo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Endocr Soc
Hauptverfasser: Yoshiji, Satoshi, Iwasaki, Yorihiro, Iwasaki, Kanako, Honjo, Sachiko, Hirano, Koichi, Ono, Katsuhiko, Yamazaki, Yuto, Sasano, Hironobu, Hamasaki, Akihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Case Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371388/
https://ncbi.nlm.nih.gov/pubmed/32715270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa051
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge