Study protocol for a randomised controlled trial evaluating the effects of the orexin receptor antagonist suvorexant on sleep architecture and delirium in the intensive care unit

INTRODUCTION: Insomnia frequently occurs in patients admitted to an intensive care unit (ICU). Sleep-promoting agents may reduce rapid eye movement sleep and have deliriogenic effects. Suvorexant (Belsomra) is an orexin receptor antagonist with Food and Drug Administration (FDA) approval for the tre...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Azimaraghi, Omid, Hammer, Maximilian, Santer, Peter, Platzbecker, Katharina, Althoff, Friederike C, Patrocinio, Maria, Grabitz, Stephanie D, Wongtangman, Karuna, Rumyantsev, Sandra, Xu, Xinling, Schaefer, Maximilian S, Fuller, Patrick M, Subramaniam, Balachundhar, Eikermann, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Anaesthesia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371384/
https://ncbi.nlm.nih.gov/pubmed/32690536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-038474
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