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Chemical genetics in drug discovery

Chemical-genetic approaches are based on measuring the cellular outcome of combining genetic and chemical perturbations in large-numbers in tandem. In these approaches the contribution of every gene to the fitness of an organism is measured upon exposure to different chemicals. Current technological...

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Détails bibliographiques
Publié dans:Curr Opin Syst Biol
Auteurs principaux: Cacace, Elisabetta, Kritikos, George, Typas, Athanasios
Format: Artigo
Langue:Inglês
Publié: Elsevier Ltd 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371212/
https://ncbi.nlm.nih.gov/pubmed/32715163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coisb.2017.05.020
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