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Anticholestatic Effect of Bardoxolone Methyl on Hepatic Ischemia-reperfusion Injury in Rats

BACKGROUND. Cholestasis is a sign of hepatic ischemia-reperfusion injury (IRI), which is caused by the dysfunction of hepatocyte membrane transporters (HMTs). As transcriptional regulation of HMTs during oxidative stress is mediated by nuclear factor erythroid 2-related factor 2, we hypothesized tha...

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Dettagli Bibliografici
Pubblicato in:Transplant Direct
Autori principali: Kim, Joohyun, Hagen, Catherine E., Kumar, Suresh N., Park, Jong-In, Zimmerman, Michael A., Hong, Johnny C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371100/
https://ncbi.nlm.nih.gov/pubmed/32766432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000001017
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