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Transient synaptic potentiation in nucleus accumbens shell during refraining from cocaine seeking.

Repeated exposure to drug-associated cues without reward (extinction) leads to refraining from drug seeking in rodents. We determined if refraining is associated with transient synaptic plasticity (t-SP) in nucleus accumbens shell (NAshell), akin to the t-SP measured in the NAcore during cue-induced...

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Veröffentlicht in:Addict Biol
Hauptverfasser: Roberts-Wolfe, Douglas J., Heinsbroek, Jasper A., Spencer, Sade M., Bobadilla, Ana Clara, Smith, Alexander C.W., Gipson, Cassandra D., Kalivas, Peter W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371007/
https://ncbi.nlm.nih.gov/pubmed/31062493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12759
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