Ultralow-input single-tube linked-read library method enables short-read second-generation sequencing systems to routinely generate highly accurate and economical long-range sequencing information

Long-range sequencing information is required for haplotype phasing, de novo assembly, and structural variation detection. Current long-read sequencing technologies can provide valuable long-range information but at a high cost with low accuracy and high DNA input requirements. We have developed a s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Res
Prif Awduron: Chen, Zhoutao, Pham, Long, Wu, Tsai-Chin, Mo, Guoya, Xia, Yu, Chang, Peter L., Porter, Devin, Phan, Tan, Che, Huu, Tran, Hao, Bansal, Vikas, Shaffer, Justin, Belda-Ferre, Pedro, Humphrey, Greg, Knight, Rob, Pevzner, Pavel, Pham, Son, Wang, Yong, Lei, Ming
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2020
Pynciau:
Method
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370886/
https://ncbi.nlm.nih.gov/pubmed/32540955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.260380.119
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