Kinetic feasibility of nitroxyl reduction by physiological reductants and biological implications

Nitroxyl (HNO), the one-electron reduced and protonated congener of nitric oxide (NO), is a chemically unique species with potentially important biological activity. Although HNO-based pharmaceuticals are currently being considered for the treatment of chronic heart failure or stroke/transplant-deri...

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Udgivet i:Free Radic Biol Med
Main Authors: Jackson, Matthew I., Han, Tae H., Serbulea, Laura, Dutton, Andrew, Ford, Eleonora, Miranda, Katrina M., Houk, K.N., Wink, David A., Fukuto, Jon M.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370859/
https://ncbi.nlm.nih.gov/pubmed/19577638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.06.034
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