Prophylactic therapy with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis through immunomodulation via aggregates with peritoneal macrophages

BACKGROUND: Despite recent advances in neonatal care, sepsis remains a leading cause of mortality in neonates. Mesenchymal stem cells derived from various tissues, such as bone marrow, umbilical cord, and adipose tissue, have beneficial effects on adult sepsis. Although human amniotic fluid stem cel...

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Bibliographic Details
Published in:Stem Cell Res Ther
Main Authors: Sato, Yu, Ochiai, Daigo, Abe, Yushi, Masuda, Hirotaka, Fukutake, Marie, Ikenoue, Satoru, Kasuga, Yoshifumi, Shimoda, Masayuki, Kanai, Yae, Tanaka, Mamoru
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370504/
https://ncbi.nlm.nih.gov/pubmed/32690106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01809-1
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