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SUV39H1-DNMT3A-mediated epigenetic regulation of Tim-3 and galectin-9 in the cervical cancer

BACKGROUND: Methylation of histone 3 at lysine 9 (H3K9) and DNA methylation are epigenetic marks correlated with genes silencing. The tumor microenvironment significantly influences therapeutic responses and clinical outcomes. The epigenetic-regulation mechanism of the costimulatory factors Tim-3 an...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Zhang, Li, Tian, Sijuan, Zhao, Minyi, Yang, Ting, Quan, Shimin, Yang, Qing, Song, Lihua, Yang, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370487/
https://ncbi.nlm.nih.gov/pubmed/32699524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01380-y
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