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Integrin α5β1 inhibition by ATN-161 reduces neuroinflammation and is neuroprotective in ischemic stroke
Stroke remains a leading cause of death and disability with limited therapeutic options. Endothelial cell β(1) integrin receptors play a direct role in blood-brain barrier (BBB) dysfunction through regulation of tight junction proteins and infiltrating leukocytes, potentially mediated by β1 integrin...
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| Pubblicato in: | J Cereb Blood Flow Metab |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
SAGE Publications
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7370357/ https://ncbi.nlm.nih.gov/pubmed/31575337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X19880161 |
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