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Inhibition of Ovarian Cancer Cell Spheroid Formation by Synthetic Peptides Derived from Nectin-4

The formation of 3D multicellular spheroids in the ascites fluid of ovarian cancer patients is an understudied component of the disease progression. Spheroids are less sensitive to chemotherapy, in part due to the protection afforded by their structure, but also due to their slower proliferation rat...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Boylan, Kristin L.M., Manion, Rory D., Shah, Heena, Skubitz, Keith M., Skubitz, Amy P. N.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370299/
https://ncbi.nlm.nih.gov/pubmed/32629816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134637
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