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Robust and Scalable Angiogenesis Assay of Perfused 3D Human iPSC-Derived Endothelium for Anti-Angiogenic Drug Screening

To advance pre-clinical vascular drug research, in vitro assays are needed that closely mimic the process of angiogenesis in vivo. Such assays should combine physiological relevant culture conditions with robustness and scalability to enable drug screening. We developed a perfused 3D angiogenesis as...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: van Duinen, Vincent, Stam, Wendy, Mulder, Eva, Famili, Farbod, Reijerkerk, Arie, Vulto, Paul, Hankemeier, Thomas, van Zonneveld, Anton Jan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370283/
https://ncbi.nlm.nih.gov/pubmed/32645937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134804
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