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Robust and Scalable Angiogenesis Assay of Perfused 3D Human iPSC-Derived Endothelium for Anti-Angiogenic Drug Screening

To advance pre-clinical vascular drug research, in vitro assays are needed that closely mimic the process of angiogenesis in vivo. Such assays should combine physiological relevant culture conditions with robustness and scalability to enable drug screening. We developed a perfused 3D angiogenesis as...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: van Duinen, Vincent, Stam, Wendy, Mulder, Eva, Famili, Farbod, Reijerkerk, Arie, Vulto, Paul, Hankemeier, Thomas, van Zonneveld, Anton Jan
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370283/
https://ncbi.nlm.nih.gov/pubmed/32645937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134804
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