Nicotinamide Phosphoribosyltransferase (Nampt)/Nicotinamide Adenine Dinucleotide (NAD) Axis Suppresses Atrial Fibrillation by Modulating the Calcium Handling Pathway

Aging and obesity are the most prominent risk factors for onset of atrial fibrillation (AF). Nicotinamide phosphoribosyltransferase (Nampt) is the rate-limiting enzyme that catalyzes nicotinamide adenine dinucleotide (NAD) activity. Nampt and NAD are essential for maintenance of cellular redox homeo...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Feng, Duo, Xu, DongZhu, Murakoshi, Nobuyuki, Tajiri, Kazuko, Qin, Rujie, Yonebayashi, Saori, Okabe, Yuta, Li, Siqi, Yuan, Zixun, Aonuma, Kazutaka, Ieda, Masaki
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370160/
https://ncbi.nlm.nih.gov/pubmed/32629939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134655
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