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Cytotoxic Effect of Vanicosides A and B from Reynoutria sachalinensis against Melanotic and Amelanotic Melanoma Cell Lines and in silico Evaluation for Inhibition of BRAFV600E and MEK1

Vanicosides A and B are the esters of hydroxycinnamic acids with sucrose, occurring in a few plant species from the Polygonaceae family. So far, vanicosides A and B have not been evaluated for anticancer activity against human malignant melanoma. In this study, we tested these two natural products,...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Nawrot-Hadzik, Izabela, Choromańska, Anna, Abel, Renata, Preissner, Robert, Saczko, Jolanta, Matkowski, Adam, Hadzik, Jakub
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370030/
https://ncbi.nlm.nih.gov/pubmed/32610527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134611
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