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The Novel gem-Dihydroperoxide 12AC3O Suppresses High Phosphate-Induced Calcification via Antioxidant Effects in p53LMAco1 Smooth Muscle Cells

The excessive intake of phosphate (Pi), or chronic kidney disease (CKD), can cause hyperphosphatemia and eventually lead to ectopic calcification, resulting in cerebrovascular diseases. It has been reported that reactive oxygen species (ROS), induced by high concentrations of Pi loading, play a key...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Takase, Naoko, Inden, Masatoshi, Hirai, Shunsuke, Yamada, Yumeka, Kurita, Hisaka, Takeda, Mitsumi, Yamaguchi, Eiji, Itoh, Akichika, Hozumi, Isao
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369805/
https://ncbi.nlm.nih.gov/pubmed/32610684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134628
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