Extracellular Matrix Stiffness and Composition Regulate the Myofibroblast Differentiation of Vaginal Fibroblasts

Fibroblast to myofibroblast differentiation is a key feature of wound-healing in soft tissues, including the vagina. Vaginal fibroblasts maintain the integrity of the vaginal wall tissues, essential to keep pelvic organs in place and avoid pelvic organ prolapse (POP). The micro-environment of vagina...

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Udgivet i:Int J Mol Sci
Main Authors: Ruiz-Zapata, Alejandra M., Heinz, Andrea, Kerkhof, Manon H., van de Westerlo-van Rijt, Cindy, Schmelzer, Christian E. H., Stoop, Reinout, Kluivers, Kirsten B., Oosterwijk, Egbert
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369731/
https://ncbi.nlm.nih.gov/pubmed/32635512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134762
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