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Impaired ECM Remodeling and Macrophage Activity Define Necrosis and Regeneration Following Damage in Aged Skeletal Muscle

Regenerative capacity of skeletal muscle declines with age, the cause of which remains largely unknown. We investigated extracellular matrix (ECM) proteins and their regulators during early regeneration timepoints to define a link between aberrant ECM remodeling, and impaired aged muscle regeneratio...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Rahman, Fasih Ahmad, Angus, Sarah Anne, Stokes, Kyle, Karpowicz, Phillip, Krause, Matthew Paul
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369722/
https://ncbi.nlm.nih.gov/pubmed/32605082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134575
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