Iron Deficiency Anemia at Time of Vaccination Predicts Decreased Vaccine Response and Iron Supplementation at Time of Vaccination Increases Humoral Vaccine Response: A Birth Cohort Study and a Randomized Trial Follow-Up Study in Kenyan Infants

Background: Iron deficiency may impair adaptive immunity and is common among African infants at time of vaccination. Whether iron deficiency impairs vaccine response and whether iron supplementation improves humoral vaccine response is uncertain. Methods: We performed two studies in southern coastal...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Stoffel, Nicole U., Uyoga, Mary A., Mutuku, Francis M., Frost, Joe N., Mwasi, Edith, Paganini, Daniela, van der Klis, Fiona R. M., Malhotra, Indu J., LaBeaud, A. Desiráe, Ricci, Cristian, Karanja, Simon, Drakesmith, Hal, King, Charles H., Zimmermann, Michael B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369313/
https://ncbi.nlm.nih.gov/pubmed/32754150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01313
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