Pyrroloquinoline quinone can prevent chronic heart failure by regulating mitochondrial function

BACKGROUND: Myocardial mitochondrial dysfunction is the leading cause of chronic heart failure (CHF). Increased reactive oxygen species (ROS) levels, disruption of mitochondrial biogenesis and mitochondrial Ca(2+)([Ca(2+)]m) homeostasis and reduction of the mitochondrial membrane potential (ΔΨm) cau...

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Publicat a:Cardiovasc Diagn Ther
Autors principals: Xu, Xuan, Chen, Chu, Lu, Wen-Jiang, Su, Yi-Ling, Shi, Jia-Yu, Liu, Yu-Chen, Wang, Li, Xiao, Chen-Xi, Wu, Xiang, Lu, Qi
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369269/
https://ncbi.nlm.nih.gov/pubmed/32695625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/cdt-20-129
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