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Ultrasensitive Detection of Attomolar Protein Concentrations by Dropcast Single Molecule Assays

Measurements of very low levels of biomolecules, including proteins and nucleic acids, remain a critical challenge in many clinical diagnostic applications due to insufficient sensitivity. While digital measurement methods such as Single Molecule Arrays (Simoa), or digital ELISA, have made significa...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Wu, Connie, Garden, Padric M., Walt, David R.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368998/
https://ncbi.nlm.nih.gov/pubmed/32602703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c04331
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