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Schizophrenia and Epigenetic Aging Biomarkers: Increased Mortality, Reduced Cancer Risk, and Unique Clozapine Effects

BACKGROUND: Schizophrenia (SZ) is associated with increased all-cause mortality, smoking, and age-associated proteins, yet multiple previous studies found no association between SZ and biological age using Horvath’s epigenetic clock, a well-established aging biomarker based on DNA methylation (DNAm)...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Higgins-Chen, Albert T., Boks, Marco P., Vinkers, Christiaan H., Kahn, René S., Levine, Morgan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368835/
https://ncbi.nlm.nih.gov/pubmed/32199607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2020.01.025
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