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Effect of Inhaled Cannabis for Pain in Adults With Sickle Cell Disease: A Randomized Clinical Trial

IMPORTANCE: Sickle cell disease (SCD) is characterized by chronic pain and episodic acute pain caused by vasoocclusive crises, often requiring high doses of opioids for prolonged periods. In humanized mouse models of SCD, a synthetic cannabinoid has been found to attenuate both chronic and acute hyp...

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Detalhes bibliográficos
Publicado no:JAMA Netw Open
Main Authors: Abrams, Donald I., Couey, Paul, Dixit, Niharika, Sagi, Varun, Hagar, Ward, Vichinsky, Elliott, Kelly, Mary Ellen, Connett, John E., Gupta, Kalpna
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368173/
https://ncbi.nlm.nih.gov/pubmed/32678452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2020.10874
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