Effect of Inhaled Cannabis for Pain in Adults With Sickle Cell Disease: A Randomized Clinical Trial

IMPORTANCE: Sickle cell disease (SCD) is characterized by chronic pain and episodic acute pain caused by vasoocclusive crises, often requiring high doses of opioids for prolonged periods. In humanized mouse models of SCD, a synthetic cannabinoid has been found to attenuate both chronic and acute hyp...

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Publicado en:JAMA Netw Open
Autores principales: Abrams, Donald I., Couey, Paul, Dixit, Niharika, Sagi, Varun, Hagar, Ward, Vichinsky, Elliott, Kelly, Mary Ellen, Connett, John E., Gupta, Kalpna
Formato: Artigo
Lenguaje:Inglês
Publicado: American Medical Association 2020
Materias:
Original Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368173/
https://ncbi.nlm.nih.gov/pubmed/32678452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2020.10874
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