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Characterization of the N(6)-etheno-bridge method to assess extracellular metabolism of adenine nucleotides: detection of a possible role for purine nucleoside phosphorylase in adenosine metabolism

The goal of this study was to determine the validity of using N(6)-etheno-bridged adenine nucleotides to evaluate ecto-nucleotidase activity. We observed that the metabolism of N(6)-etheno-ATP versus ATP was quantitatively similar when incubated with recombinant CD39, ENTPD2, ENTPD3, or ENPP-1, and...

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Vydáno v:Purinergic Signal
Hlavní autoři: Jackson, Edwin K., Gillespie, Delbert G., Cheng, Dongmei, Mi, Zaichuan, Menshikova, Elizabeth V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367995/
https://ncbi.nlm.nih.gov/pubmed/32367441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-020-09699-x
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