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P2X7 siRNA targeted to the kidneys increases klotho and delays the progression of experimental diabetic nephropathy

Previous studies in our laboratory have suggested that P2X7 could contribute to the progression of diabetic nephropathy and modulated klotho expression. The aim of this study was to investigate if P2X7 receptor is related to the expression of klotho in the onset of diabetic nephropathy in rats. Seve...

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Dettagli Bibliografici
Pubblicato in:Purinergic Signal
Autori principali: Rodrigues, A. M., Serralha, R. S., Lima, D. Y., Punaro, G. R., Visona, I., Fernandes, M. J. S., Higa, E. M. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367965/
https://ncbi.nlm.nih.gov/pubmed/32377919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-020-09695-1
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