(-)-Epigallocatechin-3-Gallate Inhibits eNOS Uncoupling and Alleviates High Glucose-Induced Dysfunction and Apoptosis of Human Umbilical Vein Endothelial Cells by PI3K/AKT/eNOS Pathway

INTRODUCTION: Diabetes can increase the risk of cardiovascular disease. This study aimed to explore the effect of (-)-epigallocatechin-3-gallate (EGCG) on high glucose (HG)-induced dysfunction and apoptosis of vascular endothelial cells. MATERIALS AND METHODS: The viability of human umbilical vein e...

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Veröffentlicht in:Diabetes Metab Syndr Obes
Hauptverfasser: Zhang, Zhiyong, Zhang, Daimin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367934/
https://ncbi.nlm.nih.gov/pubmed/32765028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S260901
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