GADL1 is a multifunctional decarboxylase with tissue-specific roles in β-alanine and carnosine production

Carnosine and related β-alanine–containing peptides are believed to be important antioxidants, pH buffers, and neuromodulators. However, their biosynthetic routes and therapeutic potential are still being debated. This study describes the first animal model lacking the enzyme glutamic acid decarboxy...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Mahootchi, Elaheh, Cannon Homaei, Selina, Kleppe, Rune, Winge, Ingeborg, Hegvik, Tor-Arne, Megias-Perez, Roberto, Totland, Christian, Mogavero, Floriana, Baumann, Anne, Glennon, Jeffrey Colm, Miletic, Hrvoje, Kursula, Petri, Haavik, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367687/
https://ncbi.nlm.nih.gov/pubmed/32733999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb3713
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