Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation

ABC transporters facilitate the movement of diverse molecules across cellular membranes, but how their activity is regulated post-translationally is not well understood. Here we report the crystal structure of MlaFB from E. coli, the cytoplasmic portion of the larger MlaFEDB ABC transporter complex,...

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Vydáno v:eLife
Hlavní autoři: Kolich, Ljuvica R, Chang, Ya-Ting, Coudray, Nicolas, Giacometti, Sabrina I, MacRae, Mark R, Isom, Georgia L, Teran, Evelyn M, Bhabha, Gira, Ekiert, Damian C
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2020
Témata:
Structural Biology and Molecular Biophysics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367683/
https://ncbi.nlm.nih.gov/pubmed/32602838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60030
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