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Can Denosumab be used in combination with Doxorubicin in Osteosarcoma?
Osteosarcoma is an aggressive bone tumor of the pediatric age. It is therefore important to improve conventional therapies (chemotherapy and surgery). Anticancer drugs often cause osteoporosis due to a misbalance of RANK/RANK-L/OPG pathway. Denosumab is a monoclonal antibody with high affinity and s...
Shranjeno v:
| izdano v: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Impact Journals LLC
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7367655/ https://ncbi.nlm.nih.gov/pubmed/32733647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27669 |
| Oznake: |
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