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Global activation of oncogenic pathways underlies therapy resistance in diffuse midline glioma
Diffuse midline gliomas (DMGs) are aggressive pediatric brain tumors with dismal prognosis due to therapy-resistant tumor growth and invasion. We performed the first integrated histologic/genomic/proteomic analysis of 21 foci from three pontine DMG cases with supratentorial dissemination. Histone H3...
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| Publicado no: | Acta Neuropathol Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7367358/ https://ncbi.nlm.nih.gov/pubmed/32680567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00992-9 |
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