NFI Transcription Factors Provide Chromatin Access to Maintain Stem Cell Identity While Preventing Unintended Lineage Fate Choices

Tissue homeostasis and regeneration rely upon resident stem cells (SCs), whose behavior is regulated through niche-dependent crosstalk. The mechanisms underlying SC identity are still unfolding. Here, using spatiotemporal gene ablation in murine hair follicles (HFs), we uncover a critical role for t...

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Publicado no:Nat Cell Biol
Main Authors: Adam, Rene C., Yang, Hanseul, Ge, Yejing, Infarinato, Nicole R., Gur-Cohen, Shiri, Miao, Yuxuan, Wang, Ping, Zhao, Yilin, Lu, Catherine P., Kim, Jeong E., Ko, Joo Y., Paik, Seung S., Gronostajski, Richard M., Kim, Jaehwan, Krueger, James G., Zheng, Deyou, Fuchs, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367149/
https://ncbi.nlm.nih.gov/pubmed/32393888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-0513-0
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