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Whole-Cell Photobleaching Reveals Time-Dependent Compartmentalization of Soluble Proteins by the Axon Initial Segment

By limiting protein exchange between the soma and the axon, the axon initial segment (AIS) enables the segregation of specific proteins and hence the differentiation of the somatodendritic compartment and the axonal compartment. Electron microscopy and super-resolution fluorescence imaging have prov...

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Pubblicato in:Front Cell Neurosci
Autori principali: Nicholson, LaShae, Gervasi, Nicolas, Falières, Thibault, Leroy, Adrien, Miremont, Dorian, Zala, Diana, Hanus, Cyril
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366827/
https://ncbi.nlm.nih.gov/pubmed/32754013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00180
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