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Inactivating mutations in genes encoding for components of the BAF/PBAF complex and immune-checkpoint inhibitor outcome

Alterations of genes encoding subunits of the BAF/PBAF complexes are among the most frequent gene aberrations in human cancer. Such alterations have been shown to have an impact on tumor microenvironnement and on the capacity of tumors to respond to immune-checkpoint inhibitors (ICI). We analysed th...

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Publicado en:Biomark Res
Autores principales: Courtet, Kevin, Laizet, Yec’han, Lucchesi, Carlo, Bessede, Alban, Italiano, Antoine
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366303/
https://ncbi.nlm.nih.gov/pubmed/32695398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-020-00206-3
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