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In vivo High-Content Screening in Zebrafish for Developmental Nephrotoxicity of Approved Drugs

Despite widespread drug exposure, for example during gestation or in prematurely born children, organ-specific developmental toxicity of most drugs is poorly understood. Developmental and functional abnormalities are a major cause of kidney diseases during childhood; however, the potential causal re...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Westhoff, Jens H., Steenbergen, Petrus J., Thomas, Laurent S. V., Heigwer, Jana, Bruckner, Thomas, Cooper, Ledean, Tönshoff, Burkhard, Hoffmann, Georg F., Gehrig, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366291/
https://ncbi.nlm.nih.gov/pubmed/32754590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00583
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