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Transplanted Human Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Support Liver Regeneration in Gunn Rats

Gunn rats bear a mutation within the uridine diphosphate glucuronosyltransferase-1a1 (Ugt1a1) gene resulting in high serum bilirubin levels as seen in Crigler-Najjar syndrome. In this study, the Gunn rat was used as an animal model for heritable liver dysfunction. Induced mesenchymal stem cells (iMS...

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Bibliografiske detaljer
Udgivet i:Stem Cells Dev
Main Authors: Spitzhorn, Lucas-Sebastian, Kordes, Claus, Megges, Matthias, Sawitza, Iris, Götze, Silke, Reichert, Doreen, Schulze-Matz, Peggy, Graffmann, Nina, Bohndorf, Martina, Wruck, Wasco, Köhler, Jan Philipp, Herebian, Diran, Mayatepek, Ertan, Oreffo, Richard O.C., Häussinger, Dieter, Adjaye, James
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc., publishers 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366275/
https://ncbi.nlm.nih.gov/pubmed/30280963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2018.0010
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