Structure-based virtual screening of phytochemicals and repurposing of FDA approved antiviral drugs unravels lead molecules as potential inhibitors of coronavirus 3C-like protease enzyme

Coronaviruses are enveloped positive-strand RNA viruses belonging to family Coronaviridae and order Nidovirales which cause infections in birds and mammals. Among the human coronaviruses, highly pathogenic ones are Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) and the Middle East Respirat...

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Detalhes bibliográficos
Publicado no:J King Saud Univ Sci
Main Authors: Bahadur Gurung, Arun, Ajmal Ali, Mohammad, Lee, Joongku, Abul Farah, Mohammad, Mashay Al-Anazi, Khalid
Formato: Artigo
Idioma:Inglês
Publicado em: The Author(s). Published by Elsevier B.V. on behalf of King Saud University. 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366079/
https://ncbi.nlm.nih.gov/pubmed/32837113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jksus.2020.07.007
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