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Therapeutic Effects of Simultaneous Delivery of Nerve Growth Factor mRNA and Protein via Exosomes on Cerebral Ischemia

Stroke is the leading neurological cause of death and disability all over the world, with few effective drugs. Nerve growth factor (NGF) is well known for its multifaceted neuroprotective functions post-ischemia. However, the lack of an efficient approach to systemically deliver bioactive NGF into i...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Yang, Jialei, Wu, Shipo, Hou, Lihua, Zhu, Danni, Yin, Shimin, Yang, Guodong, Wang, Yongjun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7365960/
https://ncbi.nlm.nih.gov/pubmed/32682291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.06.013
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