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Lack of association between the CCR5-delta32 polymorphism and neurodegenerative disorders

OBJECTIVE: Recent studies have suggested that diminished Ccr5 functioning have an effect on synaptic plasticity and hippocampal memory in mouse models. CCR5-delta32, a 32-bp frameshift deletion in human CCR5 encoding a nonfunctional receptor, has been reported to have a protective effect against HIV...

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Detalhes bibliográficos
Publicado no:Alzheimer Dis Assoc Disord
Main Authors: Wojta, Kevin, Ayer, Ariane, Ramos, Eliana Marisa, Nguyen, Peter D., Karydas, Anna M., Yokoyama, Jennifer S., Kramer, Joel, Lee, Suzee E., Boxer, Adam, Miller, Bruce L., Coppola, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7365743/
https://ncbi.nlm.nih.gov/pubmed/31972607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WAD.0000000000000367
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