c-Src functionality controls self-renewal and glucose metabolism in MCF7 breast cancer stem cells

Deregulation of Src kinases is associated with cancer. We previously showed that SrcDN conditional expression in MCF7 cells reduces tumorigenesis and causes tumor regression in mice. However, it remained unclear whether SrcDN affected breast cancer stem cell functionality or it reduced tumor mass. H...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Mayoral-Varo, Víctor, Calcabrini, Annarica, Sánchez-Bailón, María Pilar, Martínez-Costa, Óscar H., González-Páramos, Cristina, Ciordia, Sergio, Hardisson, David, Aragón, Juan J., Fernández-Moreno, Miguel Ángel, Martín-Pérez, Jorge
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7365443/
https://ncbi.nlm.nih.gov/pubmed/32673341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235850
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