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全反式维甲酸对NPM1突变的白血病细胞系U937细胞的作用及其机制研究

OBJECTIVE: To investigate the effect and mechanism of all-trans retinoic acid (ATRA) on leukemic cell line U937 cells with NPM1 mutation. METHODS: Human acute myeloid leukemia cell line U937 was explored, NPM1 mutated (A type) plasmids were transfected into U937 to form stable clones A1 and A2, whic...

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Detalhes bibliográficos
Publicado no:Zhonghua Xue Ye Xue Za Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial office of Chinese Journal of Hematology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7364968/
https://ncbi.nlm.nih.gov/pubmed/29166739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3760/cma.j.issn.0253-2727.2017.10.008
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