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Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance
BACKGROUND: Tumors can evolve and adapt to therapeutic pressure by acquiring genetic and epigenetic alterations that may be transient or stable. A precise understanding of how such events contribute to intratumoral heterogeneity, dynamic subpopulations, and overall tumor fitness will require experim...
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| 發表在: | Genome Biol |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7364565/ https://ncbi.nlm.nih.gov/pubmed/32669109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02085-1 |
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