Effect of Rotigotine vs Placebo on Cognitive Functions Among Patients With Mild to Moderate Alzheimer Disease: A Randomized Clinical Trial

IMPORTANCE: Impairment of dopaminergic transmission may contribute to cognitive dysfunction in Alzheimer disease (AD). OBJECTIVE: To investigate whether therapy with dopaminergic agonists may affect cognitive functions in patients with AD. DESIGN, SETTING, AND PARTICIPANTS: This phase 2, monocentric...

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Detalhes bibliográficos
Publicado no:JAMA Netw Open
Main Authors: Koch, Giacomo, Motta, Caterina, Bonnì, Sonia, Pellicciari, Maria Concetta, Picazio, Silvia, Casula, Elias Paolo, Maiella, Michele, Di Lorenzo, Francesco, Ponzo, Viviana, Ferrari, Clarissa, Scaricamazza, Eugenia, Caltagirone, Carlo, Martorana, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2020
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7364345/
https://ncbi.nlm.nih.gov/pubmed/32667654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2020.10372
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