Development of Natural-Based Bone Cement for a Controlled Doxorubicin-Drug Release

Osteosarcoma (OS) accounts for 60% of all global bone cancer diagnoses. Intravenous administration of Doxorubicin Hydrochloride (DOXO) is the current form of OS treatment, however, systemic delivery has been linked to the onset of DOXO induced cardiomyopathy. Biomaterials including calcium phosphate...

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Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Dewhurst, Rebecca Marie, Scalzone, Annachiara, Buckley, Joseph, Mattu, Clara, Rankin, Kenneth S., Gentile, Piergiorgio, Ferreira, Ana Marina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Bioengineering and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363953/
https://ncbi.nlm.nih.gov/pubmed/32733869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00754
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