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Mitofusin 2 Dysfunction and Disease in Mice and Men

A causal relationship between Mitofusin (MFN) 2 gene mutations and the hereditary axonal neuropathy Charcot-Marie-Tooth disease type 2A (CMT2A) was described over 15 years ago. During the intervening period much has been learned about MFN2 functioning in mitochondrial fusion, calcium signaling, and...

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Publicat a:Front Physiol
Autor principal: Dorn, Gerald W.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363930/
https://ncbi.nlm.nih.gov/pubmed/32733278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00782
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