Cross-serotype protection against group A Streptococcal infections induced by immunization with SPy_2191

Group A Streptococcus (GAS) infection causes a range of diseases, but vaccine development is hampered by the high number of serotypes. Here, using reverse vaccinology the authors identify SPy_2191 as a cross-protective vaccine candidate. From 18 initially identified surface proteins, only SPy_2191 i...

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Pubblicato in:Nat Commun
Autori principali: Sanduja, Pooja, Gupta, Manish, Somani, Vikas Kumar, Yadav, Vikas, Dua, Meenakshi, Hanski, Emanuel, Sharma, Abhinay, Bhatnagar, Rakesh, Johri, Atul Kumar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363907/
https://ncbi.nlm.nih.gov/pubmed/32669564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17299-x
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