CLIC2α Chloride Channel Orchestrates Immunomodulation of Hemocyte Phagocytosis and Bactericidal Activity in Crassostrea gigas

Chloride ion plays critical roles in modulating immunological interactions. Herein, we demonstrated that the anion channel CLIC2α mediates Cl(−) flux to regulate hemocytes functions in the Pacific oyster (Crassostrea gigas). Specifically, during infection by Vibrio parahemolyticus, chloride influx w...

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Udgivet i:iScience
Main Authors: Zhang, Xiangyu, Mao, Fan, Wong, Nai-Kei, Bao, Yongbo, Lin, Yue, Liu, Kunna, Li, Jun, Xiang, Zhiming, Ma, Haitao, Xiao, Shu, Zhang, Yang, Yu, Ziniu
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363696/
https://ncbi.nlm.nih.gov/pubmed/32674055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101328
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